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(J) Western blotting determined the protein expression and quantitation of ZO-1, Occludin, and Claudin-1

Using biodegradable polymeric nanoparticles (NPs) engineered for TAM targeting via CD206 mannose receptor binding, researchers delivered in vitro -transcribed mRNA encoding IRF5, a transcription factor crucial for M1 polarization, and its activating kinase, IKK